Azelastine, a generic anti-histamine medication, has previously been identified as a potential anti-COVID-19 drug by CEBINA in collaboration with Professor Robert Konrat, a renowned structural biologist (Department of Structural and Computational Biology, University of Vienna, Austria) who applied a novel computational prediction approach and Professor Ferenc Jakab and his group (Head of National Laboratory of Virology at the Szentágothai Research Centre, University of Pécs, Hungary), providing experimental confirmation.
The potent anti-SARS-CoV-2 activity of azelastine formulated in a nasal spray was demonstrated in an experimental reconstituted human nasal tissue model and was evident at a lower dose than present in commercially available products.
CEBINA is planning a proof-of-concept clinical trial to confirm the efficacy of azelastine against nasal colonization and is in discussion with potential licensing partners for worldwide production and distribution of an anti-COVID-19 azelastine nasal spray.
CivicaScript launches droxidopa for symptomatic neurogenic orthostatic hypotension
Padagis' Naloxone HCl Nasal Spray 4 mg obtains extended shelf-life of 36 months
ANI Pharmaceuticals announces US launch of Nitazoxanide Tablets
Newbury Pharmaceuticals secures approval for Macitentan in Denmark
Mallinckrodt and Endo to merge in USD6.7bn deal to create pharmaceutical leader
Genomma Lab Internacional announces quarterly dividend
Aveva Drug Delivery systems introduces generic Fentanyl Transdermal Patch in US
Independent Pharmacy Cooperative signs cooperation agreement with Legacy Pharmacy Group
ILIKOS Consulting partners with Jordan Center for Pharmaceutical Research
Axsome Therapeutics settles patent litigation with Teva over AUVELITY
Breckenridge Pharmaceutical's Everolimus Tablets for Oral Suspension receive US FDA approval
Newbury Pharmaceuticals secures generic approval for pomalidomide in Denmark
Newbury Pharmaceuticals secures generic approval for Bosutinib in Norway
Guangzhou Fermion Technology partners with Simcere Pharmaceutical