Clinical-stage life sciences company ZYUS Life Sciences Corporation (TSXV:ZYUS) on Thursday reported favourable preliminary results from its ongoing Phase 2a UTOPIA-1 (Unique Treatment of Oncology Pain in Advanced Cancer) trial evaluating Trichomylin softgel capsules in patients experiencing moderate to severe cancer-related pain.
UTOPIA-1, a single-arm, proof-of-concept study, is designed to investigate the safety and preliminary analgesic efficacy of Trichomylin softgel capsules in patients with advanced cancer and moderate to severe cancer-related pain.
Preliminary results from the Phase 2a trial are based on data from the first 25% of enrolled patients that have completed treatment in the UTOPIA-1 trial. The company says that early data suggest a reduction in average daily pain, pain interference, and pain severity, and a reduction in opioid dosing for breakthrough pain. There were no serious adverse events related to Trichomylin softgel capsules, and the product was generally well tolerated.
"While the data remains early, the signals we are seeing reinforce our belief that Trichomylin softgel capsules have the potential to address cancer-related pain through a non-opioid alternative and support our continued efforts to generate robust clinical evidence," said Brent Zettl, CEO of ZYUS.
Compass Pathways wins FDA IND acceptance for COMP360 PTSD trial
Merck completes acquisition of Cidara Therapeutics for USD9.2bn
HUTCHMED reports positive Phase III results for sovleplenib in wAIHA
GSK reports positive phase III results for bepirovirsen in chronic hepatitis B
Bambusa Therapeutics reports first patient dosed in proof-of-concept COPD trial
Health Canada approves AbbVie's eight-week MAVIRET regimen for acute and chronic hepatitis C
Cartography Biosciences partners with Pfizer to discover tumour-selective antigens
Nimbus Therapeutics partners with Lilly to develop oral obesity treatment
BioArctic and Eisai secure Chinese acceptance for subcutaneous Leqembi filing
Oculis secures FDA Breakthrough Therapy Designation for Privosegtor in optic neuritis
Nanjing Delova Biotech reports positive Phase 3 trial results for QP-6211 for postoperative pain
MetaVia reports positive results from Phase 1 clinical trial in obesity
RedHill advances RHB-102 across GI indications
Halozyme licenses ENHANZE to Skye Bioscience for nimacimab obesity programme