United States-based Puma Biotechnology has signed an exclusive license agreement with Canada-based Knight Therapeutics to grant the latter the exclusive right to commercialise NERLYNX (neratinib) in Canada, it was reported yesterday.
The company filed a new drug submission for NERLYNX with Health Canada in July 2018 for the extended adjuvant treatment of adult patients with early stage HER2-overexpressed/amplified breast cancer following adjuvant trastuzumab-based therapy.
According to the terms of the License Agreement, Knight will be responsible for all commercial activities and future regulatory submissions for NERLYNX in Canada. Puma will receive upfront and milestone payments up to USD7.2m throughout the term of this agreement, and double digit royalties on net sales of NERLYNX in Canada.
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